Conference Description
Key Takeaways
- Nexus Conference 2026 focuses on operational resilience for mission-critical infrastructure and cyber-physical systems in the context of artificial intelligence, regulatory changes and geopolitical tensions.
- The event takes place November 3 to 5, 2026, at the Hyatt Regency Capitol Hill in Washington, DC.
- Key themes include programmatic protection strategies that integrate people, processes and technology rather than relying solely on security solutions.
- Topics span cyber resilience, cybersecurity insurance, operational technology security, vulnerability management and compliance.
- The conference is hosted by Claroty and targets cybersecurity leaders from industrial, healthcare and government sectors.
About the Event
Nexus Conference 2026 is Claroty’s annual thought leadership event for cybersecurity professionals responsible for protecting cyber-physical systems (CPS) and operational technology (OT) environments. The conference brings together security leaders from industrial companies, healthcare delivery organizations and government agencies to share best practices on CPS cybersecurity, protection and resilience strategies.
The 2025 edition of the conference convened more than 250 cybersecurity leaders. Past speakers have included Charles Carmakal (CTO, Mandiant), Chris Inglis (former U.S. National Cyber Director) and Samantha Jacques (VP Clinical Engineering, McLaren Health Care).
Key Topics
The conference addresses operational resilience as artificial intelligence becomes a prominent tool in protecting operational technology and cyber-physical systems. Sessions explore how defenders can use AI to correlate operational signals at machine speed and make context-informed judgments about changes to facilities.
Additional topics covered through the Nexus platform include cybersecurity insurance considerations (including ransomware coverage and war exclusions), zero trust frameworks for OT environments, technical debt in operational technology, asset inventory management and third-party remote access security.
Industry and Regulatory Context
The conference addresses the intersection of cybersecurity with insurability and compliance requirements. Content explores how organizations can ensure their protection programs meet evolving regulatory standards while maintaining coverage eligibility with cybersecurity insurers. Healthcare organizations face particular scrutiny with anticipated changes to the HIPAA Security Rule, while industrial sectors navigate requirements such as IEC 62443 for OT security.
Who Should Attend
The event targets CISOs, security engineers and operational technology professionals from critical infrastructure sectors including healthcare, manufacturing, food and beverage, and federal government. Attendees typically hold responsibility for protecting industrial control systems, medical devices, building management systems and other cyber-physical systems.

